Endocrine Abstracts

According to recent views, underlying cause and characteristic of type 2 diabetes mellitus (DM2), complicated by non-alcoholic fatty liver disease (NAFLD) is chronic systemic low-gradient inflammation, in which the leading role in liver damage and DM2 decompensation is given to the cytokine production. The purpose of this study was to compare the levels of interleukin 17 (IL-17) expression in patients with DM2 and NAFLD, as well as to assess the relationship between IL-17 and ...

One of the leading roles in the mechanisms of type 2 diabetes mellitus (T2DM) belongs to immunopathological link of pathogenesis, which determines the development rate and severity of its specific complications, in particular, non-alcoholic fatty liver disease (NAFLD).The purpose: To examine the contents of cytokines and major lymphocyte subsets in patients with T2DM and NAFLD.Description of methods: We observed 118 patients, inclu...

Association of type 2 diabetes, NAFLD, intestinal dysbiosis and endotoxemia is a trigger factor of cytokine cascade which manifest in proinflammatory state development, insulin resistance, hyperglycemia and dyslipidemia progression. The aim of this study is to reveal the effect of multiprobiotic Symbiter (symbiotic association of 14–24 strains of Bifidobacterium Lactobacillus, Propionibacterium, Lactococcus lactis, Streptococcus, Acetobacter aceti) and hepatoprotector Glu...